There is no substitute for functional data.
We design and synthesize NGS-verified pools of millions of protein variants, ready for your high-throughput assay.
Protein optimization is a search problem.
The functional sequence space is enormous, and the signal is sparse. Random mutagenesis scales to millions of variants but stays close to a single parent sequence. Rational design reaches more diverse candidates, but synthesis costs have kept it to small batches. Most of the productive space goes untested.
Designed, synthesized, and verified.
1K–5M
Variants per pool
120–2500 AA
360–7500 BP coding
3–4 weeks
Design to delivery
NGS verified
Every pool
You send us your starting protein. Three to four weeks later, you receive a tube. Your screening platform stays exactly as it is.
Case Study
Case Study: BM3 Hydroxylase
3.2M
Designs
57–97%
AA identity range
3,159–3,297 BP
DNA length
We chose BM3 hydroxylase because it’s a real target — used in industrial biocatalysis — and a hard one. At ~1,075 amino acids, designing and building millions of variants in a single pool is a stress test for the platform.
Early Access Program
Work with us
Fee-for-service. No subscription. No lock-in.
IP transfer fees waived for EAP partners.
Applications open through June 2026.
Contact
Tell us about your protein and the throughput of your assay. We’ll respond within two business days.
Or email us directly at contact@talariabio.com